MAGUS study has been enrolling participants at the local clinic for treatment of genital ulcer disease (GUD) beginning Monday 27th June 2022. Swabs of the genital ulcer are collected to test for likely causes of genital ulcer which include herpes simplex virus, Treponema pallidum and Haemophilus ducreyi.
Participants are offered a urine test for Chlamydia trachomatis (CT) and Neisseria gonorrhoea (NG) even those that are asymptomatic. The female participants are offered a Trichomonas vaginalis (TV) test from a self-administered vaginal swab which is performed as with released point-of-care in a matter of 15 minutes. Treatment for TV is offered in the event a participant is found with a positive result.
All participants with a GUD syndrome are treated as per the Zimbabwe STI treatment guidelines. Participants with a positive urine test to CT and or NG are treated.
To date, 55 participants have been enrolled from 2 sites. Enrolment of participants will begin at 2 more sites in October 2022.
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